Recognized as the purest replication of Lombard-Romanesque architecture in the United States, the exterior brick walls were laid using a medieval technique. The interior features extensive use of ceramics including floor tiles, pillars and altar baldachino.

The unique architectural style of Blessed Trinity makes it stand out from other churches in Western New York. In the early 1920s, the second pastor of Blessed Trinity, Rev. Albert Pritton, wanted to build a new church like those found in northern Italy using the Lombard-Romanesque style.

Construction began in 1923 and the church was dedicated in 1928. The unmolded bricks of the church were hand-made using medieval methods and tools. The odd shapes and sizes of each brick required the architect, Chester Oakley to provide special training for the experienced bricklayers.

Rev. Thomas Plassman, president of St. Bonaventure University designed the medieval iconography for the church. There are over 2000 symbols and pictures in terra-cotta tiles, paintings and sculpture.